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Anthrax:
Overview for Health Care Providers
One page summary of:
Organism/stability, Infective dose, Natural reservoir,
Route of infection, Communicability, Risk factors, Case
fatality, Incubation period, Clinical manifestations,
Laboratory tests
Anthrax:
Guidance for Health Care Providers
Key Medical and Public Health Interventions After Identification
of a Suspected Case
What is anthrax?
Anthrax is a disease caused by bacteria that create spores. People
can get sick when spores enter the body. Spores can enter the body
in different ways and cause different types of illness. When the
spores enter through a cut or sore, a skin infection can occur.
When the spores are breathed in, they may cause serious breathing
problems. When they are in meat that is not cooked enough before
it is eaten, an illness of the intestine may result.
Who gets anthrax?
Anthrax occurs naturally in certain wild and domestic animals (e.g.,
cattle, sheep, goats, camels, antelopes, and other herbivores),
most commonly in South and Central America, Southern and Eastern
Europe, Asia and Africa. Anthrax occurs occasionally in animal herds
in the United States. It can also occur in humans who come into
contact with infected animals or contaminated animal products (e.g.,
hides, hair, wool, bone, bone products, and wool).
How is anthrax spread?
Spread of anthrax from one person to another is extremely rare.
People get sick when they come in contact with spores that are in
the soil and in animals or animal products in parts of the world
where the disease occurs.
Could anthrax be used for bioterrorism?
Yes. Anthrax is one of the agents that could be used for bioterrorism
because it could cause increased illness and death in the population
if used as a weapon. In September 2001 in the United States, anthrax
spores were sent to several locations through the mail. Twenty-two
people got sick, five of whom died. Information about ways to identify
suspicious mail can be found on the U.S. Postal Service website
at www.usps.com.
What are the symptoms of anthrax?
The symptoms of anthrax are different, depending on the type of
exposure. When the spores enter through a cut or sore, a painless
lesion appears, which eventually forms a black center. Swelling
of lymph glands close to the lesion may occur. When the spores are
breathed in, symptoms may resemble influenza and without early treatment,
may progress to severe breathing problems and even death. When infected
meat is eaten, initial symptoms are nausea, loss of appetite, vomiting,
followed by abdominal pain, vomiting of blood and severe diarrhea.
How soon after exposure do symptoms
appear?
Symptoms usually appear within 1 to 7 days after exposure, but the
time period may vary depending on how the spores enter the body.
How is it diagnosed and treated?
Anthrax is diagnosed through special laboratory tests. Samples may
be taken from different parts of the body, depending on the type
of anthrax (e.g., blood, skin lesions, or respiratory secretions).
Specific antibiotics can be prescribed by a doctor to treat anthrax.
To be effective, treatment should start immediately. If left untreated,
the disease can be fatal. The most serious type of anthrax happens
when the spores are breathed in.
What can be done to prevent the spread
of anthrax?
Vaccination of people in high-risk occupations can reduce the spread
of anthrax (see below). Careful handling of dead animals suspected
of having anthrax; providing good ventilation (air flow) when processing
hides, fur, hair or wool; and vaccinating animals can help prevent
anthrax. If a person has had a known exposure to anthrax, vaccination
and/or antibiotics may prevent the disease.
Is there a vaccine for anthrax?
There is a vaccine for anthrax, but it is recommended only for the
following groups: 1. People who work with anthrax in a laboratory;
2. People who work with animal hides or furs imported from high-risk
areas; 3. People who will have repeated exposures to anthrax spores
(e.g., workers investigating areas contaminated from a bioterrorist
attack); 4. People who handle animal products in high-risk areas
(e.g., veterinarians who travel to work in countries where anthrax
incidence is higher); and 5. Military personnel who work in areas
where anthrax could be used as a bioterrorism weapon.
The vaccine is not currently recommended for others.